Upgrades between minor versions of the agent, like from 2.1 to 2.2 are always backwards compatible. Upgrades that involve a major version bump often come with some backwards incompatible changes.
Before upgrading the agent, be sure to review the:
End of life datesedit
We love all our products, but sometimes we must say goodbye to a release so that we can continue moving forward on future development and innovation. Our End of life policy defines how long a given release is considered supported, as well as how long a release is considered still in active development or maintenance.